Interested in learning more? Contact us:
1900 599 927
  • EN
    VI
  • My cart
  • My account
    Sign in
  • Genetic reports
  • Genetic consultation
  • Saliva Collecting Guide
  • Partners
  • Blog
  • News
  • 1900 599 927
  • EN
    VI
  • < Home
    /
    Blog
    /

    Genetic factors influencing sexual activity

    06/04/2020
    Fertility

    Genetic variants associated with the age at which a person first engages in sexual intercourse are reported in a paper published online this week in Nature Genetics. The study sheds light on how the timing of puberty may affect age at first sexual intercourse (AFS), and how both affect social and health outcomes.

    AFS has been correlated with a number of social and behavioral factors, such as social disadvantage and family instability. Genetic factors also contribute to AFS and related traits, including age at first birth (AFB) in women, although the extent of this contribution is unknown. Genetic variants associated with timing of puberty - which has decreased from an average age of 18 years in 1880 to 12.5 years in 1980 - in both men and women have been recently identified, and some studies have reported a correlation between puberty timing and AFS, suggesting that they may also be correlated at the genetic level.

    Ken Ong, John Perry and colleagues conducted a genome-wide association study of more than 125,000 participants (59,357 men and 66,310 women aged 40-69 years) from the UK Biobank study and identified 38 variants associated with AFS. They then replicated these findings in 241,910 men and women from Iceland and 20,187 healthy American women (aged greater than 45 years) of European-ancestry from the Women’s Genome Health Study.

    The authors found that both AFS and AFB have a moderate genetic component and that both are independently genetically correlated with timing of puberty. The authors used a statistical method called Mendelian randomization to infer a causal effect of puberty timing on AFS and AFB (i.e., earlier puberty leads to earlier AFS and AFB). They also predicted causal effects of all three traits on social and behavioral outcomes, such as educational attainment.

    Some of the variants associated with AFS were located in or near genes that have been previously implicated in risk-taking propensity, irritable temperament, number of children, and processes and traits related to brain development. However, whether any of these genes are involved in regulating the timing of puberty, AFS or AFB remains to be determined.

    Reference: https://www.natureasia.com/en/research/highlight/10634

    Dinh dưỡng và sự phát triển thể chất của trẻ

    15/01/2021

    Tính cách và sự hình thành tính cách ở trẻ

    14/01/2021

    Các bệnh ở trẻ thường gặp vào mùa đông xuân và cách phòng tránh

    12/01/2021

    Những điều cần biết khi trẻ bị sốt

    11/01/2021
    • About Us

    • Contact

    • Frequently Asked Questions

    • Terms of Service

    • Privacy Policy

    • Career

    • General Transaction Conditions

    • Service Delivery Process

    • Payment Methods

    • Return & Complaint-Handling Policy

    US Head Office

    1011 23rd St.
    Unit 15
    San Francisco, CA 94107

    Singapore Office

    16 Raffles Quay
    #33-03 Hong Leong Building
    Singapore (048581)

    Hà Nội Office

    4th Floor, Viet Tower Building,
    1 Thai Ha Street, Dong Da District

    Hồ Chí Minh City

    6F, Song Do Building,
    62A Pham Ngoc Thach Street, Ward 6, Dist. 3

  • Facebook
  • Youtube
  • LinkedIn
  • 1900 599 927 | cs@genetica.asia

    Download Genetica App

    App Store
    App Store
    © Copyright 2020 | GENE FRIEND VIETNAM, INC.
    6F, 62A Pham Ngoc Thach Street, Ward 6, Dist. 3, HCMC.
    Business registration number: 0108276596.